Bioterrorism and CBRN:
Preparedness, Response and Capacity

Fellowship Concentration


The concentration in Bioterrorism and CBRNE is available to all fellows and is focused on exploring the medical effects and response to biological, chemical, and nuclear/radiological threats with a special emphasis on bioterrorism attacks. The concentration will include a current analysis of surge capacity and the potential effects of a major bioterrorism/CBRN attack. It will also evaluate the content area of modern Pandemics using both Pandemic Influenza and Ebola as case studies for bioterrorism preparedness.
This concentration will move from addressing the threats to individuals through the spectrum of the threats facing communities and evaluate the potential medical and system outcomes for both. Specifically, we will address both individual treatment strategies of disease, and larger community and national outcomes and response strategies.


  • Understand Medical Effects and Therapeutics for Biological, Chemical, and Nuclear/Radiation Threats; special emphasis on Bioterrorism
  • Evaluate Novel Detection approaches and Therapies for Biothreats
  • Analyze Bioterrorism Preparedness Strategies
  • Analyze Surge Capacity and how it impacts the threat potential within Biodefense
  • Evaluate Novel Approaches to expanding surge capacity and response capabilities
  • Evaluate Modern Day Pandemics and Pandemic response strategies


The structure will broadly consist of a guided study through a modular topic review.
We will follow the module outline below to cover the topics and will typically focus on one topic a month. We will plan to meet once per month for discussion, review, and case studies.
This concentration is designed to be helpful and informative to the Fellow and therefore is flexible to meet his/her needs or interests as they arise.

Concentration Module

Module 1 & 2 – Jan and Feb
  • Medical Effects and Therapeutics: Biological Threats
  • Novel Detection and Therapies for Biothreats
  • Case Study: 2001 Anthrax Attack (Amerithrax)
  • Identify presentations of medical effects
Module 3 – March
  • Medical Effects and Therapeutics: Chemical Threats
  • Medical Effects and Therapeutics: Radiation/ Blast Injuries Threats
  • Case Study: Tokyo Sarin Attacks
  • Case Study: Japan Reactor Criticality Accident 2011; Chernobyl Reactor Criticality Accident
Module 4 – April
Surge Capacity Framework for Bioterrorism
  • Surge Capacity: What is it? Why is it important to CBRNE Threats? How do we achieve it?
  • Novel Approaches to Surge and Response Capacity
  • Community and National Preparedness Efforts
  • Case Study: Hurricane Katrina and Sandy
  • Case Study: Tokyo Sarin Attacks Revisited
Module 5 – May
Modern Day Threats: Pandemics
  • Influenza: Preparation, Response, and Outcomes
  • Ebola: Preparation, Response and Outcomes

Reading Materials

Textbook References

Additional Materials:

These are not required reading- we will be reading small sections of some and the other sources included here are for your own personal supplemental reference. Will be provided in dropbox format for your download.

  1. BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats: Abbreviated Version
  2. Institute of Medicine (IOM) Medical Surge Capacity
  3. Assessing Medical Preparedness to Respond to a Terrorist Nuclear Event
  4. Centers for Disease Control and Prevention. Public Health Emergency Response Guide for State, Local, and Tribal Public Health Directors. CDC, 2010.
  5. Crisis Standards of Care: A Systems Framework for Catastrophic Disaster Response
  6. Medical Surge Capacity Handbook: A Management System for Integrating Medical and Health Resources During Large-Scale Emergencies.
  7. National Strategy for Pandemic Influenza
  8. National Strategy for Countering Biological Threats
  9. Ready or Not? Protecting the Public’s Health from Diseases, Disasters, and Bioterrorism. Trust for America’s Health Robert Wood Johnson Foundation, 2010.
  10.  The Next Challenge in Healthcare Preparedness: Catastrophic Health Events. Center for Biosecurity of UPMC.
  11. Healthcare coalitions: The new foundation for national healthcare preparedness and response for catastrophic health emergencies.
  12. Hospital-Based Emergency Care: At the Breaking Point